WEKO3
アイテム
Gender differences in the association of high-sensitivity C-reactive protein with metabolic syndrome and diabetes mellitus in a Japanese population: Jichi Medical School Cohort Study II
https://jichi-ir.repo.nii.ac.jp/records/1023
https://jichi-ir.repo.nii.ac.jp/records/10236dcc3489-df22-4909-85db-3332b4b94d0c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
自治医科大学紀要 1881-252X(43)p21-29 2021 (191.1 kB)
|
.png)
|
| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2021-05-13 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Gender differences in the association of high-sensitivity C-reactive protein with metabolic syndrome and diabetes mellitus in a Japanese population: Jichi Medical School Cohort Study II | |||||||||||||||
| 言語 | en | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | cohort study | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | diabetes mellitus | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | gender differences | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | high-sensitivity C-reactive protein | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | metabolic syndrome | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||||||
| 著者 |
Hino, Yumika
× Hino, Yumika
× Ae, Ryusuke
× Eshima, Nobuoki
× Nakamura, Yosikazu
× Ishikawa, Shizukiyo
|
|||||||||||||||
| 著者別名 | ||||||||||||||||
| 姓名 | 日野, 有美香 | |||||||||||||||
| 言語 | ja | |||||||||||||||
| 著者別名 | ||||||||||||||||
| 姓名 | 阿江, 竜介 | |||||||||||||||
| 言語 | ja | |||||||||||||||
| 著者別名 | ||||||||||||||||
| 姓名 | 江島, 伸興 | |||||||||||||||
| 言語 | ja | |||||||||||||||
| 著者別名 | ||||||||||||||||
| 姓名 | 中村, 好一 | |||||||||||||||
| 言語 | ja | |||||||||||||||
| 著者別名 | ||||||||||||||||
| 姓名 | 石川, 鎮清 | |||||||||||||||
| 言語 | ja | |||||||||||||||
| 抄録 | ||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||
| 内容記述 | Background Recently, some studies showed that metabolic syndrome (MetS) is associated with inflammation, indicated by high-sensitivity C-reactive protein (hsCRP), but there have been few population-based studies, especially in Japan. Herein, gender-specific relationships between MetS, diabetes mellitus (DM) and hsCRP in a general Japanese population were examined. Methods This cross-sectional study included 6436 males and females examined between 2010 and 2017 as part of the Jichi Medical School Cohort Study Ⅱ. Total subjects were divided into tertiles according to hsCRP values and the odds ratios (ORs) in MetS and DM were compared by gender. Results There exists a dose–response relationship between hsCRP levels and prevalence of MetS in both males and females. The conditional (adjusted) ORs of DM for given MetS status were not statistically significant, on the other hand, all the conditional ORs of MetS for given DM status were statistically significant (p<0.01) for both males and females (males: ORs for the second and third tertiles, DM- 1.7[95% confidence interval, 1.2-2.4], 2.4[1.8-3.4], DM+ 2.8[1.8-4.2], 3.1[2.1-4.5]; females: DM- 3.2[1.9-5.4], 5.4[3.2-9.9], DM+ 2.9[1.6-5.4], 4.2[2.3-7.5]). Furthermore, it was statistically shown that the conditional ORs of females are greater than those of males (female-to-male ratios of ORs for the second and third tertiles, 1.9, p=0.023; 2.2, p=0.005). Conclusion Inflammation, as measured by hsCRP, was elevated in both males and females with MetS in this Japanese population; however, hsCRP was elevated in patients with DM, probably because of high prevalence of MetS in patients with DM. hsCRP is a more suitable predictor of MetS for females than males. |
|||||||||||||||
| 書誌情報 |
自治医科大学紀要 en : Jichi Medical University Journal 巻 43, p. 21-29, 発行日 2021-03 |
|||||||||||||||
| 出版者 | ||||||||||||||||
| 出版者 | 自治医科大学 | |||||||||||||||
| ISSN | ||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||
| 収録物識別子 | 1881-252X | |||||||||||||||
