WEKO3
アイテム
Ultrastr uctural study of the undulated epithelial side of glomer ular basement membrane in membranousnephropathy；clinicopathological study of 20 patients
https://jichi-ir.repo.nii.ac.jp/records/83
https://jichi-ir.repo.nii.ac.jp/records/83057390d5-d2e9-43d1-8652-70d849a1bc74
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
自治医科大学紀要 1881-252X 第37巻 p11-18 2015.3 (310.4 kB)
|
.png)
|
| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2015-05-12 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Ultrastr uctural study of the undulated epithelial side of glomer ular basement membrane in membranousnephropathy；clinicopathological study of 20 patients | |||||||||||||
| 言語 | en | |||||||||||||
| その他（別言語等）のタイトル | ||||||||||||||
| その他のタイトル | 膜性腎症症例の中で超微形態にて糸球体基底膜にうねりを示す20例の臨床病理学的検討 | |||||||||||||
| 言語 | ja | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Complement | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | electron micrograph | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | glomerular basement membrane | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | membranous nephropathy | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | renal biopsy | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||||
| 著者 |
Suzuki, Tsukasa
× Suzuki, Tsukasa
× Maeda, Masayuki
× Yoshimoto, Taichiro
× Fukushima1, Noriyoshi
|
|||||||||||||
| 著者別名 | ||||||||||||||
| 姓名 | 鈴木, 司 | |||||||||||||
| 言語 | ja | |||||||||||||
| 著者別名 | ||||||||||||||
| 姓名 | 前田, 真之 | |||||||||||||
| 言語 | ja | |||||||||||||
| 著者別名 | ||||||||||||||
| 姓名 | 吉本, 多一郎 | |||||||||||||
| 言語 | ja | |||||||||||||
| 著者別名 | ||||||||||||||
| 姓名 | 福嶋, 敬宣 | |||||||||||||
| 言語 | ja | |||||||||||||
| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Introduction: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults and is characterized by electron-dense deposits (EDD) in the glomerular basement membrane (GBM). On the other hand, undulations, which are formed on the epithelial side of the GBM irrelevant to EDD, are observed in some cases; these findings were not considered in the Ehrenreich and Churg (EC) classification in MN. Methods: Twenty adult patients with MN formed long segments of undulations on the epithelial side of the GBM without reactions to subepithelial EDD by EM were enrolled. We compared the clinicopathological findings of these cases with 20 control cases of MN patients who did not have this undulation. These two patient groups were matched for gender, age, and class of disease stage in the EC classification of MN. Results: In the study group, the lamina densa thickened in many areas in comparison with the control group (962.4±309.1 vs. 604.0±296.5 nm; p=0.001). In addition, the number of C3c positive cases were less in the immunofluorescence (IF) study, (n=4 vs. n=12; p=0.009), and serum complement levels tended to be higher than those in the control group. Conclusion: In our study, the pathogenesis of GBM undulation was not determined. Nevertheless, these results indicate that diverse immune responses, in addition to the complement system, may be involved differently from usual cases of MN. |
|||||||||||||
| 書誌情報 |
自治医科大学紀要 en : Jichi Medical University Journal 巻 37, p. 11-18, 発行日 2015-03 |
|||||||||||||
| 出版者 | ||||||||||||||
| 出版者 | 自治医科大学 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 1881-252Ｘ | |||||||||||||
