Item type |
紀要論文 / Departmental Bulletin Paper(1) |
公開日 |
2014-05-28 |
タイトル |
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タイトル |
Risk of Cerebral Infarction assessed by Fasting Insulin and Fasting Glucose in a Japanese General Population: The Jichi Medical School Cohort Study |
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言語 |
en |
言語 |
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言語 |
jpn |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Cerebral infarction |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
fasting insulin |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
fasting glucose |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
cohort study |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
departmental bulletin paper |
著者 |
Kaneda, Yuji
Ishikawa, Shizukiyo
Goto, Tadao
Kayaba, Kazunori
Yasuda, Yoshikazu
Kajii, Eiji
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抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
This study was performed to examine the relation between the risk of cerebral infarction and fasting insulin (FI) stratified by fasting glucose (FG) in a Japanese general population. The subjects were 2,608 men and women, examined between 1992 and 1995 as part of the Jichi Medical School Cohort Study. Subjects were divided into nine groups; group1 (G1) with tertile 1 (T1) of FI and T1 of FG, G2 with T2 of FI and T1 of FG , G3 with T3 of FI and T1 of FG, G4 with T1 of FI and T2 of FG, G5 with T2 of FI and T2 of FG, G6 with T3 of FI and T2 of FG, G7 with T1 of FI and T3 of FG, G8 with T2 of FI and T3 of FG and G9 with T3 of FI and T3 of FG. Cox’s proportional hazard model was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for cerebral infarction. During an average of 11.1 years of follow-up, 87 participants developed cerebral infarction. In multivariate-adjusted analysis, HRs of cerebral infarction were 3.93 (95% CI, 1.13–13.72) in G1, 2.30 (0.51–10.34) in G3, 2.19 (0.58–8.19) in G4, 1.18 (0.26–5.31) in G5, 2.96 (0.81–10.88) in G6, 3.48 (0.97–12.53) in G7, 2.39 (0.66–8.62) in G8 and 3.73 (1.09–12.84) in G9, using G2 as the reference. The association between FI and risk of cerebral infarction seemed to be U-shaped and this association was seen in each FG level. |
書誌情報 |
自治医科大学紀要
en : Jichi Medical University Journal
巻 36,
p. 33-40,
発行日 2014-03
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出版者 |
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出版者 |
自治医科大学 |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1881-252X |