| Item type |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2023-06-09 |
| タイトル |
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|
タイトル |
Intraperitoneal administration of paclitaxel combined with S-1 plus oxaliplatin followed by conversion surgery in a patient with stage IV gastric cancer and intestinal malrotation: Report of a case. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Administration of paclitaxel |
| キーワード |
|
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Case report |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Conversion Surgery |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Intraperitoneal Intestinal malrotation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Stage IV gastric cancer |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 著者 |
Fujinuma, Kae
Saito, Shin
Yamaguchi, Hironori
Kanamaru, Rihito
Ohzawa, Hideyuki
Kurashina, Kentaro
Hosoya, Yoshinori
NaSano, Naoki
Niki, Toshiro
Kawarai Lefor, Alan
Kitayama, Joji
Sata, Naohiro
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| 著者別名 |
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姓名 |
藤沼, 香栄 |
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言語 |
ja |
| 著者別名 |
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姓名 |
齋藤, 心 |
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言語 |
ja |
| 著者別名 |
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姓名 |
山口, 博紀 |
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言語 |
ja |
| 著者別名 |
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姓名 |
金丸, 理人 |
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言語 |
ja |
| 著者別名 |
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姓名 |
大澤, 英之 |
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言語 |
ja |
| 著者別名 |
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姓名 |
倉科, 憲太郎 |
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言語 |
ja |
| 著者別名 |
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姓名 |
細谷, 好則 |
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言語 |
ja |
| 著者別名 |
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姓名 |
佐野, 直樹 |
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言語 |
ja |
| 著者別名 |
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姓名 |
仁木, 利郎 |
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言語 |
ja |
| 著者別名 |
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姓名 |
Kawarai Lefor, Alan |
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|
言語 |
en |
| 著者別名 |
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姓名 |
北山, 丈二 |
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言語 |
ja |
| 著者別名 |
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姓名 |
佐田, 尚宏 |
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言語 |
ja |
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: The prognosis of patients with stage IV gastric cancer remains unsatisfactory despite recent advances in multidisciplinary therapy. Asymptomatic intestinal malrotation in adults is rare and usually diagnosed incidentally by imaging or during abdominal surgery. Intestinal malrotation associated with primary gastric cancer is extremely rare. We report here a patient with stage IV gastric cancer and intestinal malrotation successfully treated with induction chemotherapy followed by gastrectomy.
Case presentation: The patient is a 57-year-old woman diagnosed with gastric cancer with peritoneal metastases. Staging laparoscopy showed disseminated nodules on the peritoneal surface with a peritoneal cancer index score of 15 points. Peritoneal fluid cytology was class V. The patient was treated with intraperitoneal administration of paclitaxel combined with S-1 plus oxaliplatin. After twelve courses of combined chemotherapy, 2nd look laparoscopy showed that peritoneal metastases were not macroscopically present and cytological examination of peritoneal washing fluid was negative for malignant cells. Total gastrectomy with regional lymph node dissection was then performed. Pathological examination of the specimen revealed grade 1b efficacy of IP-PTX plus SOX chemotherapy. She also had the non-rotation type of malrotation. Anatomical anomalies could cause difficulties for lymph node dissection and reconstruction during the gastrectomy against gastric cancers. The postoperative course was uneventful. Following resection, the patient received 14 courses of the same combined chemotherapy without oxaliplatin. She has done well for more than 6months after resection without evidence of recurrence.
Discussion: This is the first report of successful conversion surgery for a patient with stage IV gastric cancer and intestinal malrotation after intraperitoneal administration of paclitaxel combined with S-1 plus oxaliplatin. Gastrectomy performed after an excellent response to combined chemotherapy of peritoneal metastases may contribute to improved patient outcomes. Establishing the diagnosis of intestinal malrotation preoperatively in adults is necessary to safely perform abdominal surgery. |
| 書誌情報 |
自治医科大学紀要
en : Jichi Medical University Journal
巻 45,
p. 67-72,
発行日 2023-03
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| 出版者 |
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出版者 |
自治医科大学 |
| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
1881-252X |
自治医科大学紀要 1881-252X(45)P67-72 2023 (325.2 kB)
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