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  1. 紀要論文
  2. 自治医科大学紀要第45巻

Determinants of extracellular fluid after hemodialysis in CKD stage G5D patients measured by the bioelectrical impedance (BIA) method: A propensity score matching study

https://jichi-ir.repo.nii.ac.jp/records/1272
https://jichi-ir.repo.nii.ac.jp/records/1272
4ab8840d-b507-4eef-94f7-0cb79e032cc6
名前 / ファイル ライセンス アクション
自治医科大学紀要 自治医科大学紀要 1881-252X(45)P1-10 2023 (160.2 kB)
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Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2023-06-09
タイトル
タイトル Determinants of extracellular fluid after hemodialysis in CKD stage G5D patients measured by the bioelectrical impedance (BIA) method: A propensity score matching study
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Bioimpedance
キーワード
言語 en
主題Scheme Other
主題 Extracellular body water
キーワード
言語 en
主題Scheme Other
主題 Hemodialysis
キーワード
言語 en
主題Scheme Other
主題 Propensity score matching
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
著者 Murakami, Takuya

× Murakami, Takuya

en Murakami, Takuya

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Saito, Osamu

× Saito, Osamu

en Saito, Osamu

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Saito, Takako

× Saito, Takako

en Saito, Takako

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Ueno, Koshi

× Ueno, Koshi

en Ueno, Koshi

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Akimoto, Tetsu

× Akimoto, Tetsu

en Akimoto, Tetsu

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Nagata, Daisuke

× Nagata, Daisuke

en Nagata, Daisuke

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著者別名
姓名 村上, 琢哉
言語 ja
著者別名
姓名 齋藤, 修
言語 ja
著者別名
姓名 齋藤, 孝子
言語 ja
著者別名
姓名 上野, 公司
言語 ja
著者別名
姓名 秋元, 哲
言語 ja
著者別名
姓名 長田, 太助
言語 ja
抄録
内容記述タイプ Abstract
内容記述 Background: Hemodialysis patients have a higher incidence of extracellular edema than patients with a normal renal function, even if their dry weight (DW) setting is appropriate. However, the factors determining post-dialysis edema in hemodialysis patients have not been fully elucidated. We investigated the determinants of post-dialysis ECW/TBW index (ratio of extracellular body water to total body water) in hemodialysis patients and compared them with non-chronic kidney disease (non-CKD) patients.
Methods: The ECW/TBW index was measured using a bioimpedance body composition analyzer. We measured clinical parameters and the ECW/TBW index in 159 hemodialysis patients and 385 non-CKD patients. We evaluated the relationships with various clinical parameters by a multivariable linear analysis and stepwise regression analysis. Differences in age and BMI between the hemodialysis and non-CKD patients were adjusted by propensity score matching. The modified groups were analyzed by multivariable linear analysis and stepwise regression analyses.
Results: The ECW/TBW index was significantly higher in the hemodialysis patients. A multivariable linear analysis with the ECW/TBW index as the objective variable showed significant associations in age, pre-dialysis Hb, Ht, TP, Alb, Cr, human atrial natriuretic peptide (HANP) and percent creatinine generation rate (%CGR) in hemodialysis patients. After propensity score matching for age and BMI, a strong effect of age was observed in the non-CKD patients, while Alb affected the ECW/TBW index in the hemodialysis patients.
Conclusion: While age strongly influenced the ECW/TBW index in non-CKD patients, that in hemodialysis patients was more strongly influenced by serum Alb than age. High ECW/TBW index is associated with a poor prognosis in hemodialysis patients, suggesting the importance of paying attention to the pre-dialysis albumin concentration in the setting of the body fluid removal for DW.
書誌情報 自治医科大学紀要
en : Jichi Medical University Journal

巻 45, p. 1-10, 発行日 2023-03
出版者
出版者 自治医科大学
ISSN
収録物識別子タイプ PISSN
収録物識別子 1881-252X
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