@article{oai:jichi-ir.repo.nii.ac.jp:00000090,
 author = {Nagashima, Takao and Murosaki, Takamasa and Honne, Kyoko and Kamata, Yasuyuki and Nagatani, Katsuya and Iwamoto, Masahiro and Minota, Seiji},
 journal = {自治医科大学紀要, Jichi Medical University Journal},
 month = {Mar},
 note = {Objective: To investigate the association between joint symptoms and related conditions in Japanese patients with polymyositis (PM) and dermatomyositis (DM).
Methods: We retrospectively reviewed all patients with PM/DM who were admitted to our department from January 2007 to March 2012. Clinical data on these patients were retrieved from the medical records.
Results: Seventy-eight patients (20 with PM and 58 with DM) were enrolled. Among them, 37 patients (47%) had arthralgia or arthritis. Joint symptoms were more frequent in DM than PM (53% vs. 30%, P=0.07). Anti-aminoacyl tRNA antibodies (ASA) were positive in 25 patients (32%), and anti-cyclic citrullinated peptide (CCP) antibody was positive in 7 patients (9%). Patients with anti-Jo-1 antibody had a high frequency of polyarthritis (82%), while anti-CCP antibody was positive in 4 out of 11 patients with anti-Jo-1 antibody (36%). Among patients with joint symptoms, anti-Jo-1 antibody was positive in 67% of the patients with PM, but was positive in only 16% of the patients with DM. Four of the 78 patients (5%) were initially diagnosed and treated as having rheumatoid arthritis. Multivariate analysis showed that fever, Raynaud’s phenomenon, and anti-Jo-1 antibody were associated with joint symptoms, whereas overall ASA positivity showed no significant difference between patients with or without joint symptoms.
Conclusion: Forty-seven percent of patients with PM/DM had joint symptoms. Except for anti-Jo-1 antibody, ASA were not associated with joint symptoms in Japanese PM/DM patients.},
 pages = {9--16},
 title = {Articular manifestations in Japanese patients with polymyositis and dermatomyositis},
 volume = {38},
 year = {2016}
}