{"created":"2023-06-19T11:22:44.332971+00:00","id":665,"links":{},"metadata":{"_buckets":{"deposit":"3b00a2d2-a821-403e-914a-94c82ebd9145"},"_deposit":{"created_by":12,"id":"665","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"665"},"status":"published"},"_oai":{"id":"oai:jichi-ir.repo.nii.ac.jp:00000665","sets":["14:32"]},"author_link":[],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-12","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"18","bibliographicPageStart":"11","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"自治医科大学紀要"},{"bibliographic_title":"Jichi Medical University Journal","bibliographic_titleLang":"en"}]}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"IgA 腎症に対するミゾリビン（MZB）の治療効果について検討した。対象は腎生\n検が施行されたIgA 腎症例で，IgA 腎症診療指針に基づく組織学的予後不良群および\n予後不良群の中で尿蛋白が１g/ 日以上の７例に対し，MZB を24週間投与した。尿中\nNAG は開始時と比べて開始後４週（p ＝0.08）および24週（p ＝0.06）では改善傾向\nが認められ，投与後の腎機能悪化速度が投与開始前と比較し改善傾向を示すものの\n（p ＝0.052），両者とも有意差は認めなかった。尿蛋白やクレアチニンクリアランスに\nついては試験期間中に有意な変化は認めず，重篤な副作用も認めなかった。IgA 腎症に\n対するMZB 投与は，24週という短期間では腎機能悪化を阻止できない。","subitem_description_type":"Abstract"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"names":[{"name":"Iwazu, Yoshitaka","nameLang":"en"}]},{"names":[{"name":"Nakazawa, Eiko","nameLang":"en"}]},{"names":[{"name":"Kobayashi, Takahisa","nameLang":"en"}]},{"names":[{"name":"Azuma, Masahiro","nameLang":"en"}]},{"names":[{"name":"Masuda, Takahiro","nameLang":"en"}]},{"names":[{"name":"Ando, Yasuhiro","nameLang":"en"}]},{"names":[{"name":"Muto, Shigeaki","nameLang":"en"}]},{"names":[{"name":"Kusano, Eiji","nameLang":"en"}]}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"自治医科大学"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1881-252X","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"岩津, 好隆","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"中澤, 英子","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"小林, 高久","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"東, 昌広","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"増田, 貴博","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"安藤, 康宏","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"武藤, 重明","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"草野, 英二","creatorNameLang":"ja"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-13"}],"displaytype":"detail","filename":"自治医科大学紀要1881-252X(30)p11-18.pdf","filesize":[{"value":"973.4 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"自治医科大学紀要1881-252X(30)p11-18","url":"https://jichi-ir.repo.nii.ac.jp/record/665/files/自治医科大学紀要1881-252X(30)p11-18.pdf"},"version_id":"18aa59fd-7eb0-4480-a5f4-160ae8bcacd3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"IgA 腎症","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ミゾリビン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"尿細管障害","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"尿中NAG","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"予後比較的不良群と予後不良群のIgA 腎症に対するミゾリビンの有効性の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"予後比較的不良群と予後不良群のIgA 腎症に対するミゾリビンの有効性の検討","subitem_title_language":"ja"},{"subitem_title":"Efficacy of Mizoribine for Severe IgA nephropathy","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["32"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-08-13"},"publish_date":"2019-08-13","publish_status":"0","recid":"665","relation_version_is_last":true,"title":["予後比較的不良群と予後不良群のIgA 腎症に対するミゾリビンの有効性の検討"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-08-25T06:07:20.610655+00:00"}