{"created":"2023-06-19T11:22:43.592114+00:00","id":642,"links":{},"metadata":{"_buckets":{"deposit":"7f3717b9-1bf4-472d-a821-5cb721c7b0b4"},"_deposit":{"created_by":12,"id":"642","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"642"},"status":"published"},"_oai":{"id":"oai:jichi-ir.repo.nii.ac.jp:00000642","sets":["14:31"]},"author_link":[],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"40","bibliographicPageStart":"31","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"自治医科大学紀要"},{"bibliographic_title":"Jichi Medical University Journal","bibliographic_titleLang":"en"}]}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"わが国ではドナーの適応を拡大する一つの方法として，ABO 血液型不適合生体腎移植が数多く実施されている。今回，自治医科大学附属病院におけるABO 血液型不適合腎移植に対して臨床的検討を行った。\n　2003年４月から2007年12月までに当院で施行した生体腎移植54例中，ABO 血液型不適合腎移植10例を対象（ABO 不適合群）とし，同期間のABO 血液型適合腎移植44例をコントロール群（ABO 適合群）とした。\n　ABO 不適合群では，移植前１週間より導入免疫抑制薬としてタクロリムス，ミコフェノール酸モフェチル，メチルプレドニゾロンの服用を開始，抗ドナー血液型抗体に対し全例移植前に血漿交換を施行。さらに全例脾摘を施行，バシリキシマブを術当日および術後４日目に投与した。\n　2008年３月までの成績は，ABO 不適合群では生存率，生着率は各々90％，100％，ABO 適合群では97.7 ％，97.7 ％ であった。急性拒絶反応は，ABO 不適合群２例（20％），ABO 適合群12例（27.2％）に認めた。両群とも重篤な合併症は認めなかった。当院で施行したABO 血液型不適合症例は，その移植成績（患者生存，移植腎生着），急性拒絶反応発生率等において，血液型適合症例と比較し同等であった。わが国の腎移植臨床登録集計報告（2006年実施症例）によれば923例中215例（23.3％）がABO 血液型不適合症例であり，国内のドナーの現状からABO 血液型不適合症例は今後も増加する傾向にあると考えられた。","subitem_description_type":"Abstract"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"names":[{"name":"Ishikawa, Nobuo","nameLang":"en"}]},{"names":[{"name":"Sakuma, Yasunaru","nameLang":"en"}]},{"names":[{"name":"Fujiwara, takehito","nameLang":"en"}]},{"names":[{"name":"Miyamoto, Naoshi","nameLang":"en"}]},{"names":[{"name":"Nukui, Akinori","nameLang":"en"}]},{"names":[{"name":"Yashi, Masahiro","nameLang":"en"}]},{"names":[{"name":"Yagisawa, Takashi","nameLang":"en"}]}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"自治医科大学"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1881-252X","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"石川, 暢夫","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"佐久間, 康成","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"藤原, 岳人","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"宮本, 直志","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"貫井, 昭徳","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"安士, 正裕","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"八木澤, 隆","creatorNameLang":"ja"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-09-04"}],"displaytype":"detail","filename":"自治医科大学紀要1881-252X(31)p31-40.pdf","filesize":[{"value":"898.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"自治医科大学紀要1881-252X(31)p31-40","url":"https://jichi-ir.repo.nii.ac.jp/record/642/files/自治医科大学紀要1881-252X(31)p31-40.pdf"},"version_id":"1b026927-503f-4382-b6df-d9997f9969ae"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ABO 血液型不適合腎移植","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫抑制","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"脾摘","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"血漿交換","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"自治医科大学附属病院におけるABO 血液型不適合腎移植","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"自治医科大学附属病院におけるABO 血液型不適合腎移植","subitem_title_language":"ja"},{"subitem_title":"ABO-incompatible living kidney transplantation at Jichi Medical University Hospital","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["31"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-07-08"},"publish_date":"2019-07-08","publish_status":"0","recid":"642","relation_version_is_last":true,"title":["自治医科大学附属病院におけるABO 血液型不適合腎移植"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-08-25T06:06:54.379306+00:00"}