{"created":"2023-06-19T11:22:41.267908+00:00","id":535,"links":{},"metadata":{"_buckets":{"deposit":"0b15385f-8737-4428-9c4e-82a5a27d3fa1"},"_deposit":{"created_by":12,"id":"535","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"535"},"status":"published"},"_oai":{"id":"oai:jichi-ir.repo.nii.ac.jp:00000535","sets":["14:25"]},"author_link":[],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"66","bibliographicPageStart":"61","bibliographicVolumeNumber":"41","bibliographic_titles":[{"bibliographic_title":"自治医科大学紀要"},{"bibliographic_title":"Jichi Medical University Journal","bibliographic_titleLang":"en"}]}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"症例は41歳女性。当院初診３年２か月前に乳癌に対しドセタキセル治療を，２年７か月前に乳房温存術および放射線照射を受けた。２年前より右上肢リンパ浮腫を生じ，浮腫は左上肢，頸部に拡大。１年10か月前から両上肢，両手部の皮膚硬化が進行，関節拘縮へ発展し，６か月前からRaynaud現象，開口障害が出現し，当科を受診した。びまん皮膚硬化型全身性強皮症と診断し，入院の上，プレドニゾロン内服（20mg/日）を開始，進行する皮膚症状の改善目的にステロイドパルスを追加し，関節拘縮改善を認めた。本例はドセタキセル治療後の発症であり，上腕，前腕に浮腫，皮膚硬化が強く，一般の強皮症の末梢から体幹に拡がる皮膚硬化パターンと異なるため，ドセタキセル誘発皮膚硬化と考えた。一方，抗RNAポリメラーゼIII抗体陽性であり，皮膚硬化進行後にRaynaud現象を認めた経過から一般的な全身性強皮症の特徴を併せもつようになったと推測した。","subitem_description_type":"Abstract"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"names":[{"name":"Yabe, Hiroki","nameLang":"en"}]},{"names":[{"name":"Sakurai, Tadashi","nameLang":"en"}]},{"names":[{"name":"Tsutsumi, Tomomi","nameLang":"en"}]},{"names":[{"name":"Oda, Aya","nameLang":"en"}]},{"names":[{"name":"Nakamura, Toshinobu","nameLang":"en"}]},{"names":[{"name":"Yamada, Tomoko","nameLang":"en"}]},{"names":[{"name":"Demitsu, Toshio","nameLang":"en"}]},{"names":[{"name":"Kuroiwa, Takashi","nameLang":"en"}]},{"names":[{"name":"Terai, Chihiro"}]}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"自治医科大学"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1881-252X","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"矢部, 寛樹","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"桜井, 正","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"堤, 智美","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"小田, 彩","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"中村, 考伸","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"山田, 朋子","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"出光, 俊郎","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"黒岩, 卓","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"寺井, 千尋","creatorNameLang":"ja"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-04-15"}],"displaytype":"detail","filename":"自治医科大学紀要1881-252X(41)p61-66 2019.pdf","filesize":[{"value":"676.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"自治医科大学紀要1881-252X(41)p61-66 2019","url":"https://jichi-ir.repo.nii.ac.jp/record/535/files/自治医科大学紀要1881-252X(41)p61-66 2019.pdf"},"version_id":"851d01f4-6eb2-4926-a0d4-09da549afeec"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"乳癌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ドセタキセル","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"タキサン系抗癌剤","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"全身性強皮症","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"抗RNAポリメラーゼIII抗体","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"乳癌に対するドセタキセル治療後に発症した抗RNAポリメラーゼIII抗体陽性びまん皮膚硬化型全身性強皮症の一例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"乳癌に対するドセタキセル治療後に発症した抗RNAポリメラーゼIII抗体陽性びまん皮膚硬化型全身性強皮症の一例","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"12","path":["25"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-04-15"},"publish_date":"2019-04-15","publish_status":"0","recid":"535","relation_version_is_last":true,"title":["乳癌に対するドセタキセル治療後に発症した抗RNAポリメラーゼIII抗体陽性びまん皮膚硬化型全身性強皮症の一例"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-08-25T06:04:13.772614+00:00"}