@article{oai:jichi-ir.repo.nii.ac.jp:00000031,
 author = {Yamamoto, Reiko and Ishikawa, Shizukiyo and Mizooka, Masafumi and Kajii, Eiji},
 journal = {自治医科大学紀要, Jichi Medical University Journal},
 month = {Mar},
 note = {Introduction
Associations between chronic Helicobacter pylori (H.pylori) infection and cardiovascular risk factors have been demonstrated in previous studies. However, the association between H.pylori and hypertension is controversial, especially in different age groups.
Methods
We conducted this cross-sectional study to reveal the association between H.pylori seropositivity and hypertension using the Jichi Medical School (JMS) Cohort Study. Odds ratios (ORs) for hypertension were calculated using multiple logistic regression models.
Results
The prevalence of H.pylori was significantly higher in subjects with hypertension (56.1%) than those without (52.4%). H.pylori seropositivity was not associated with hypertension in overall subjects (adjusted OR: 1.14, 95% confidence interval (CI): 0.85-1.26, P=0.72). However, H.pylori seropositivity was associated with hypertension in subjects aged ≥65 years (adjusted OR: 1.30 (1.01-1.69, P=0.04), but was not in those aged<65 years.
Conclusion
There was a significant association between H.pylori seropositivity and hypertension only in subjects in the elderly, which implies that longer duration of H.pylori infection could be one of the mechanisms of hypertension.},
 pages = {13--18},
 title = {The prevalence of Helicobacter pylori with hypertension：The Jichi Medical School Cohort Study},
 volume = {35},
 year = {2013}
}