{"created":"2023-06-19T11:22:25.719510+00:00","id":20,"links":{},"metadata":{"_buckets":{"deposit":"30d6a0f4-0897-49f6-891e-dc36a55b6c88"},"_deposit":{"created_by":12,"id":"20","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"20"},"status":"published"},"_oai":{"id":"oai:jichi-ir.repo.nii.ac.jp:00000020","sets":["14:16"]},"author_link":[],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"115","bibliographicPageStart":"109","bibliographicVolumeNumber":"34","bibliographic_titles":[{"bibliographic_title":"自治医科大学紀要"},{"bibliographic_title":"Jichi Medical University Journal","bibliographic_titleLang":"en"}]}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Treatment of intravenous immunoglobulin (IVIG) resistant Kawasaki disease (KD) is challenging.\nContinuous infusion of cyclosporin A (CICyA) was employed for 4 patients with IVIG-resistant KD: these patients had remained febrile or had had recurrence of fever within 24 hours after the initial 2g/kg followed by additional 2g/kg IVIG. Response differed between initial doses of CICyA, 1.5 mg/kg/day vs. 3.0 mg/kg/day. The clinical course of the two patients treated with 1.5 mg/kg/day CICyA suggested that the low serum concentration by gradual increase of CICyA did not improve fever or inflammation. The other two patients treated with 3.0 mg/kg/day CICyA became afebrile within 24 hours after initiation of CICyA. They had a subsequently reduced dose of cyclosporin A (CyA) to maintain its appropriate serum concentration (300-500 ng/ml). No coronary artery lesion was detected one month after the onset of KD. The initial dose of 3 mg/kg/day was effective without major side effects and would be a treatment option for IVIG-resistant KD.","subitem_description_type":"Abstract"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"自治医科大学"}]},"item_2_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11819432","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1881-252X","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Minami, Takaomi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shiraishi, Hirohiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Oka, Kensuke","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Odaka, Jun","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Ishii, Tomoyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Takata, Akiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sato, Tomoyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kataoka, Koichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Morimoto, Akira","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Momoi, Mariko Y.","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2012-11-30"}],"displaytype":"detail","filename":"p109-115.pdf","filesize":[{"value":"495.7 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"p109-115","url":"https://jichi-ir.repo.nii.ac.jp/record/20/files/p109-115.pdf"},"version_id":"fa994257-30a6-4d43-a261-ec9bac01b69f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"coronary lesion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cyclosporine; immunoglobulin resistant","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Kawasaki disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Continuous Infusion of Cyclosporin A in Intravenous Immunoglobulin Resistant Kawasaki Disease Patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Continuous Infusion of Cyclosporin A in Intravenous Immunoglobulin Resistant Kawasaki Disease Patients","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["16"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2012-11-30"},"publish_date":"2012-11-30","publish_status":"0","recid":"20","relation_version_is_last":true,"title":["Continuous Infusion of Cyclosporin A in Intravenous Immunoglobulin Resistant Kawasaki Disease Patients"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-08-25T06:01:41.044423+00:00"}