{"created":"2023-06-19T11:23:02.107856+00:00","id":1287,"links":{},"metadata":{"_buckets":{"deposit":"2add1f55-a5ce-487d-9346-ec4b8082ba72"},"_deposit":{"created_by":12,"id":"1287","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"1287"},"status":"published"},"_oai":{"id":"oai:jichi-ir.repo.nii.ac.jp:00001287","sets":["14:46"]},"author_link":[],"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"90","bibliographicPageStart":"85","bibliographicVolumeNumber":"45","bibliographic_titles":[{"bibliographic_title":"自治医科大学紀要"},{"bibliographic_title":"Jichi Medical University Journal","bibliographic_titleLang":"en"}]}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"25歳の男性が数ヶ月に渡る慢性頭痛を契機に頭部MRIで下垂体腫瘤性病変を指摘され，当院脳神経外科を紹介受診し，下垂体に出血を疑わせる所見を認めたが，手術適応はないと判断された。その後半年の経過で病変は縮小を認めた。病変の鑑別としては下垂体卒中とラトケ嚢胞が考えられた。テストステロン低値，高ゴナドトロピン血症の精査のため，当科紹介受診した。入院精査にて原発性性腺機能低下症を認め，染色体分析の結果47XXYであったことからKlinefelter症候群（KFS）と診断した。合併症として骨粗鬆症を認め，基礎値や負荷試験結果よりその他の下垂体前葉機能に低下は認めなかった。退院後からテストステロン補充療法を開始した。さらに1年6ヶ月後の頭部MRIではトルコ鞍内の病変は指摘できない状態となった。自然経過で縮小した下垂体病変とKFSを合併した症例を経験したため報告する。","subitem_description_type":"Abstract"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"names":[{"name":"Watanabe, Shuhei","nameLang":"en"}]},{"names":[{"name":"Kurashina, Tomoyuki","nameLang":"en"}]},{"names":[{"name":"Igarashi, Mayuko","nameLang":"en"}]},{"names":[{"name":"Taniguchi, Ai","nameLang":"en"}]},{"names":[{"name":"Shibuya, Hiroshi","nameLang":"en"}]},{"names":[{"name":"Yamaoka, Keiko","nameLang":"en"}]},{"names":[{"name":"Saito, Shinsuke"}]},{"names":[{"name":"Oka, Kiyonori","nameLang":"en"}]},{"names":[{"name":"Sakurai, Momoe","nameLang":"en"}]},{"names":[{"name":"Koga, Yukiko","nameLang":"en"}]},{"names":[{"name":"Takahashi, Manabu","nameLang":"en"}]},{"names":[{"name":"Nagashima, Shuichi","nameLang":"en"}]},{"names":[{"name":"Okada, Kenta","nameLang":"en"}]},{"names":[{"name":"Ebihara, Ken","nameLang":"en"}]},{"names":[{"name":"Ishibashi, Shun","nameLang":"en"}]}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"自治医科大学"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1881-252X","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"渡邉, 秀平","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"倉科, 智行","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"五十嵐, 真由子","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"谷口, 亜衣","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"澁谷, 浩史","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"山岡, 桂子","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"齋藤, 新介","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"岡, 聖典","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"櫻井, 百恵","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"甲賀, 裕希子","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"髙橋, 学","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"永島, 秀一","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"岡田, 健太","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"海老原, 健","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"石橋, 俊","creatorNameLang":"ja"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-06-09"}],"displaytype":"detail","filename":"自治医科大学紀要 1881-252X(45)P85-90 2023.pdf","filesize":[{"value":"398.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"自治医科大学紀要 1881-252X(45)P85-90 2023","url":"https://jichi-ir.repo.nii.ac.jp/record/1287/files/自治医科大学紀要 1881-252X(45)P85-90 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syndrome","subitem_title_language":"en"}]},"item_type_id":"2","owner":"12","path":["46"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-06-09"},"publish_date":"2023-06-09","publish_status":"0","recid":"1287","relation_version_is_last":true,"title":["経時的に消失した下垂体病変を認めたKlinefelter 症候群の一例"],"weko_creator_id":"12","weko_shared_id":-1},"updated":"2023-08-25T06:00:55.945471+00:00"}