{"created":"2023-06-19T11:22:29.303944+00:00","id":105,"links":{},"metadata":{"_buckets":{"deposit":"3392d964-8286-4160-bb31-3521fb04e9a9"},"_deposit":{"created_by":12,"id":"105","owners":[12],"pid":{"revision_id":0,"type":"depid","value":"105"},"status":"published"},"_oai":{"id":"oai:jichi-ir.repo.nii.ac.jp:00000105","sets":["14:21"]},"author_link":["959","960","961","962","963","964","965","966","967","968","969","970","971","972","973","974"],"control_number":"105","item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"32","bibliographicPageStart":"29","bibliographicVolumeNumber":"39","bibliographic_titles":[{"bibliographic_title":"自治医科大学紀要"},{"bibliographic_title":"Jichi Medical University Journal","bibliographic_titleLang":"en"}]}]},"item_2_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"症例は慢性増殖性糸球体腎炎による慢性腎不全で両側腎移植後の62歳男性。腎移植前に慢性C型肝炎(Genotype1b）を指摘され，IFN単独療法（Peg-IFNα-2a　90μg，24週間）施行したが，治療後１年で再燃し，肝庇護剤やIFN少量長期療法で経過観察していた。直接作用型抗ウイルス薬（direct actingantivirals：DAAs）が保険適応後，Daclatasvir（ DCV）とAsunaprevir（ ASV）による治療開始とした。蜂窩織炎が増悪したため，治療開始から13日目にDAAを中断したが，sustained virologic response （SVR）を達成した。セログループ１型のC型慢性肝炎または代償性肝硬変患者に使用されているDCVとASVの併用療法は24週間投与で高いSVRが認められているが，12日間内服のみでSVRになった症例はまれであり，また腎移植後の慢性C型肝炎におけるDAAs治療は免疫抑制剤との相互併用があり，若干の文献をふまえて報告する。","subitem_description_type":"Abstract"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"Yoshinari, Takaoka","nameLang":"en"}]},{"nameIdentifiers":[{}],"names":[{"name":"Naoki, Morimoto","nameLang":"en"}]},{"nameIdentifiers":[{}],"names":[{"name":"Shunji, Watanabe","nameLang":"en"}]},{"nameIdentifiers":[{}],"names":[{"name":"Mamiko, Tsukui","nameLang":"en"}]},{"nameIdentifiers":[{}],"names":[{"name":"Takuya, Hirosawa","nameLang":"en"}]},{"nameIdentifiers":[{}],"names":[{"name":"Kozue, Murayama","nameLang":"en"}]},{"nameIdentifiers":[{}],"names":[{"name":"Norio, Isoda","nameLang":"en"}]},{"nameIdentifiers":[{}],"names":[{"name":"Hironori, Yamamoto","nameLang":"en"}]}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"自治医科大学"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1881-252X","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高岡, 良成","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"森本, 直樹","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"渡邊, 俊司","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"津久井, 舞未子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"廣澤, 拓也","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"村山, 梢","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"礒田, 憲夫","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山本, 博徳","creatorNameLang":"ja"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-06-15"}],"displaytype":"detail","filename":"自治医科大学紀要 1881-252X 第39巻 p29-32 2017.3.pdf","filesize":[{"value":"329.5 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"自治医科大学紀要 1881-252X 第39巻 p29-32 2017.3","url":"https://jichi-ir.repo.nii.ac.jp/record/105/files/自治医科大学紀要 1881-252X 第39巻 p29-32 2017.3.pdf"},"version_id":"cd6a05af-4e6b-46a7-a143-59bc79014065"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"DAAs","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"腎移植後","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"C型慢性肝炎","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"kidney transplantation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"chronic hepatitis C virus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DAAs","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin 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